Mitral valve repair vs replacement: Considerations, Techniques

The mitral valve, a critical component of the heart, ensures unidirectional blood flow from the left atrium to the left ventricle. Valve malfunction can cause significant health problems. Thankfully, advancements in cardiac surgery offer solutions, including mitral valve repair and mitral valve replacement, among others. Understanding these procedures is key to making informed heart health decisions.

Mitral valve problems typically arise from three causes: mitral regurgitation (leaky valve), mitral stenosis (narrowed valve), and prolapse (bulging of the valve flaps into the atrium). These conditions can cause symptoms like fatigue, shortness of breath, and heart palpitations. Severe cases can result in heart failure.

Mitral Valve Repair vs. Replacement: Key Considerations

Multiple factors influence the decision between mitral valve repair and replacement, including the severity of valve damage, the patient’s age, overall health, and the underlying cause of the condition.

  • Mitral Valve Repair:
  • Ideal for degenerative mitral valve disease, where the valve leaflets are still relatively healthy.
  • More likely to preserve the heart’s natural function.
  • Associated with a lower risk of complications, such as blood clots or infections.
  • Typically results in better long-term survival and fewer restrictions on physical activity.
  • Mitral Valve Replacement:
  • Necessary when the valve is severely damaged or calcified, making repair impossible.
  • Often required for advanced mitral regurgitation with significant structural damage.
  • Patients receive either a mechanical valve (requiring lifestyle modifications, including lifelong anticoagulant medication, regular blood tests, and dietary restrictions) or a biological valve (which may need replacement over time).
  • Often required for mitral stenosis, particularly when the valve is heavily calcified or fibrotic, preventing effective repair or balloon valvuloplasty.

Indications for Mitral Valve Repair vs. Replacement

The decision to proceed with mitral valve repair vs. replacement is based on a variety of factors, including:

  • Severity of Mitral Valve Disease: Mild to moderate regurgitation or prolapse is typically repaired, while severe cases may require replacement.
  • Structural Integrity of the Valve: If the mitral valve leaflets, chordae tendinae, or annulus are significantly damaged, replacement is often the best option.
  • Underlying Cause: Rheumatic disease or extensive calcification may necessitate mitral valve replacement, whereas degenerative disease is more likely an indication for repair.
  • Patient’s Age and Health Status: Younger patients benefit from repair due to durability, while older patients with multiple health issues may require replacement.

Techniques in Mitral Valve Surgery

Mitral valve surgery procedures can be performed using both traditional open-heart surgery and minimally invasive techniques. Repair procedures require specialized expertise, so choosing a surgeon with relevant experience is crucial.

  • Mitral Valve Repair Techniques

Mitral valve repair is a less invasive approach that aims to restore normal function while preserving the patient’s native valve.

Common techniques include:

  • Annuloplasty: Tightening the valve annulus (ring) to reduce leakage.
  • Leaflet Repair: Resecting or reconstructing damaged valve leaflets.
  • Chordal Repair: Replacing or shortening the chordae tendinae (supporting structures).

Transcatheter Mitral Valve Repair (TMVR), such as the MitraClip procedure, is a minimally invasive procedure that reduces mitral regurgitation by clipping the valve leaflets together. It is primarily used for patients who are not candidates for open-heart surgery. The valve is repaired using a catheter inserted through the blood vessels, avoiding a large chest incision.

While traditional mitral valve repair (MVR) surgery remains the primary treatment for mitral regurgitation, requiring a midline chest incision and open surgical repair, TMVR is emerging as a safer, less invasive alternative with promising outcomes.

  • Mitral Valve Replacement Techniques:

When repair is not viable, mitral valve replacement involves removing the damaged valve and implanting a prosthetic one. Options include:

  • Mechanical Valves: Durable and long-lasting but require lifelong blood thinners.
  • Biological Valves: Made from porcine, bovine, or human donor tissue that does not require anticoagulation but has a shorter lifespan.
  • Mitral Valve Transplant: Rarely performed, a mitral valve transplant involves replacing the diseased valve with a donor valve. In special cases, homografts (cadaveric valves) may be considered for select patients.

Conclusion

Both mitral valve repair and replacement are viable treatments for mitral valve disease, with the decision depending on the severity of the condition and individual patient factors. While repair is generally preferred due to its superior long-term outcomes, replacement is necessary in cases of severe valve damage. Advances in mitral valve surgery continue to improve success rates, offering patients a better quality of life and heart function post-procedure.